• Muhammed Keskin, Göktük İpek, Mustafa Aldağ, Servet Altay, Mert İlker Hayıroğlu, Edibe Betül Börklü, Duygu İnan, and Ömer Kozan.
• Department of Cardiology, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey. Electronic address: Drmuhammedkeskin@gmail.com.
• Nutrition. 2018 Apr 1; 48: 82-86.

ObjectivesThe prognostic effects of poor nutritional status and cardiac cachexia on coronary artery disease (CAD) are not clearly understood. A well-accepted nutritional status parameter, the prognostic nutritional index (PNI), which was first demonstrated to be valuable in patients with cancer and those undergoing gastrointestinal surgery, was introduced to patients requiring coronary artery bypass grafting (CABG). The aim of the present study was to evaluate the prognostic value of PNI in patients with CAD undergoing CABG.MethodsWe evaluated the in-hospital and long-term (3-y) prognostic effect of PNI on 644 patients with CAD undergoing CABG. Baseline characteristics and outcomes were compared among the patients by PNI and categorized accordingly: Q1, Q2, Q3, and Q4.ResultsPatients with lower PNI had significantly higher in-hospital and long-term mortality. Patients with lower PNI levels (Q1) had higher in-hospital mortality and had 12 times higher mortality rates than those with higher PNI levels (Q4). The higher PNI group had the lower rates and was used as the reference. Long-term mortality was higher in patients with lower PNI (Q1)-4.9 times higher than in the higher PNI group (Q4). In-hospital and long-term mortality rates were similar in the non-lower PNI groups (Q2-4).ConclusionThe present study demonstrated that PNI, calculated based on serum albumin level and lymphocyte count, is an independent prognostic factor for mortality in patients undergoing CABG.Copyright © 2017 Elsevier Inc. All rights reserved.

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