Medicina clinica
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Multicenter Study Observational Study
Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine.
To analyze the incidence of Covid-19 in patients who are chronic users of hydroxychloroquine. ⋯ There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19.
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Multicenter Study
Prevalence of chronic kidney disease and associated factors in the Spanish population attended in primary care: Results of the IBERICAN study.
To determine the prevalence of chronic kidney disease (CKD) and the factors associated with impaired renal function in the population attended in primary care (PC). ⋯ Fourteen out of every 100 patients included in the IBERICAN study have CKD. The prevalence of CKD affects a quarter of patients ≥ 65 years and increases exponentially with the aggregation of FRCV.
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Multicenter Study
Potential drug-drug interactions in COVID 19 patients in treatment with lopinavir/ritonavir.
To determine the prevalence of potential interactions in COVID-19 patients receiving lopinavir/ritonavir (LPV/r). The secondary objective was to develop recommendations and identify the risk factors associated with presenting potential interactions with LPV/r. ⋯ The prevalence of potential interactions in COVD-19 patient undergoing treatment with LPV/r is high, with age (> 65), ICU admission, previous respiratory and psychiatric pathology, dyslipidemia and the number of prescribed drugs acting as risk factors.
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Multicenter Study Observational Study
Autoimmune haemolytic anaemias: A retrospective study of 93 patients.
Autoimmune haemolytic anaemia (AIHA) is an infrequent and heterogeneous disease in its pathophysiology and clinical behaviour, therefore it is generally managed empirically. ⋯ We found high rates of response to steroids, with very prolonged treatments that cause side effects and corticoid dependence in a third of patients. The combination of steroids with rituximab in the first line, could be indicated in patients with low levels of haemoglobin and serological type IgG+C. The high relapse rates make necessary the development of randomised studies with new drugs or the combination with existing ones, which allow longer response times and with fewer side effects.
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Multicenter Study
Fracture risk assessment in the general population in Spain by FRAX® algorithm. EPISER2016 study.
To analyse the risk of fracture calculated by FRAX® and the frequency of high risk of fracture in the general population in Spain. ⋯ EPISER2016 enabled us to establish the risk of fracture calculated by FRAX® and the prevalence of high risk of fracture in the general population according to the different thresholds used in Spain.