Journal of neurology, neurosurgery, and psychiatry
-
J. Neurol. Neurosurg. Psychiatr. · Jul 2016
A longitudinal study of cortical grey matter lesion subtypes in relapse-onset multiple sclerosis.
Cortical grey matter (GM) lesions are common in multiple sclerosis (MS), but little is known about their temporal evolution. We investigated this in people with relapsing-remitting (RR) and secondary progressive (SP) MS. ⋯ New cortical GM lesions rarely arise from the WM and the rate of new IC lesion formation is not closely linked with WM lesion accrual. IC lesion formation appears to be more common in SPMS than RRMS.
-
J. Neurol. Neurosurg. Psychiatr. · Jul 2016
Review Meta Analysis Comparative StudyAntipsychotic medications for the treatment of delirium: a systematic review and meta-analysis of randomised controlled trials.
We performed an updated meta-analysis of antipsychotic treatment in patients with delirium, based on a previous meta-analysis published in 2007. ⋯ Our results suggested that SGAs have a benefit for the treatment of delirium with regard to efficacy and safety compared with haloperidol. However, further study using larger samples is required.