Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Apr 2008
Case ReportsA case report on fixation instability in Parkinson's disease with bilateral deep brain stimulation implants.
We report on fixation instabilities in a patient diagnosed with Parkinson's disease (PD). This patient underwent deep brain stimulation (DBS) surgery bilaterally in the vicinity of the subthalamic nuclei (STN). Examination of the eye movements of this patient revealed marked fixation instability compared with a healthy age matched control. ⋯ The frequency of these IS was higher in the patient with PD than in the healthy age matched control. Furthermore, the frequency of the IS in the patient reduced toward control with application of bilateral DBS in the vicinity of the STN. From our observations we conclude that fixation ability may be altered in PD and improved with DBS.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2008
Long-term assessment of the risk of spread in primary late-onset focal dystonia.
Primary late-onset focal dystonias may spread over time to adjacent body regions, but differences in the risk of spread over time among the various focal forms and the influence of age at dystonia onset on the risk of spread are not well established. ⋯ This study adds new insights into the phenomenon of spread of primary late-onset focal dystonia and provides the framework for future studies aimed at an indepth investigation of the mechanism(s) of spread.
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J. Neurol. Neurosurg. Psychiatr. · Mar 2008
Randomized Controlled TrialGabapentin for prevention of hypobaric hypoxia-induced headache: randomized double-blind clinical trial.
High-altitude headache (HAH) is a hypobaric hypoxia-induced symptom that is commonly experienced by newcomers to high-altitude areas. ⋯ Gabapentin was effective for the prevention of HAH and had satisfactory tolerability.
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J. Neurol. Neurosurg. Psychiatr. · Mar 2008
Mild traumatic brain injury does not predict acute postconcussion syndrome.
The aetiology of postconcussion syndrome (PCS) following mild traumatic brain injury (mTBI) remains controversial. Identifying acute PCS (within the first 14 days after injury) may optimise initial recovery and rehabilitation, identify those at risk and increase understanding of PCS. ⋯ There is a high rate of acute PCS in both mTBI and non-brain injured trauma patients. PCS was not found to be specific to mTBI. The use of the term PCS may be misleading as it incorrectly suggests that the basis of PCS is a brain injury.