Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Dec 2001
Case Reports"Fou rire prodromique" as the presentation of pontine ischaemia secondary to vertebrobasilar stenosis.
"Fou rire prodromique" (prodrome of crazy laughter) is a rare form of pathological laughter of uncertain pathophysiology. A patient is presented with pathological laughter as the first manifestation of pontine ischaemia due to vertebrobasilar stenosis. A 65 year old man developed uncontrollable and unemotional laughter for almost an hour followed by transient right facial-brachial paresis. ⋯ Necropsy confirmed the extensive brain stem infarction. Pathological laughter can be the very first presenting manifestation of ischaemia of the ventrotegmental junction of the upper pons. It is hypothesised that the pathological laughter in this patient was secondary to ischaemic ephaptic stimulation of the descending corticopontine/ bulbar pathways.
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J. Neurol. Neurosurg. Psychiatr. · Dec 2001
Prevention of spinal cord injury with time-frequency analysis of evoked potentials: an experimental study.
To verify the applicability and validity of time-frequency analysis (TFA) of evoked potential (EP) signals in detecting the integrity of spinal cord function and preventing spinal cord injury. ⋯ It was found that TFA of EPs provided an earlier and more sensitive indication of injury than time domain monitoring alone. It is suggested that TFA of EP signals should therefore be useful in preventing spinal cord injury during surgery.
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J. Neurol. Neurosurg. Psychiatr. · Dec 2001
Biography Historical ArticleThe subthalamic nucleus and Jules Bernard Luys (1828-97).
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J. Neurol. Neurosurg. Psychiatr. · Dec 2001
Biography Historical ArticlePhineas Gage and the science of brain localisation.