Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Nov 1989
Randomized Controlled Trial Comparative Study Clinical TrialEffect of the knee-chest position on cerebral blood flow in patients undergoing lumbar spinal surgery.
The cerebral haemodynamic effect of the knee-chest position was evaluated in 15 anaesthetised patients undergoing elective lumbar disc surgery and divided into a control group (n = 8) where cerebral blood flow (CBF) was measured twice in the supine position and an experimental group (n = 7) where the first CBF was measured in the supine position and the second in the knee-chest position. CBF was measured by a modified intravenous 133xenon washout technique. Mean global CBF did not change in control group (56.1, SD 9.2 versus 52.8, SD 10.8 units) and was not significantly modified by the knee-chest posture, 51.8, SD 8.8 units versus 53.9, SD 7.4 units in the supine position. The results indicate that mean global CBF in the knee-chest position is not different from CBF in the supine position in healthy patients.
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Spectral analysis of EEG was conducted for 51 elderly delirious patients meeting the Diagnostic and Statistical Manual of Mental Disorders III (DSM-III) criteria and for 19 controls. As a whole group, and also when subdivided according to the type of delirium, severity of cognitive decline or the type of central nervous system disease, delirious patients showed significant reductions of alpha percentage, increased theta and delta activity and slowing of the peak and mean frequencies and these changes were also obvious in individual recordings. The alpha percentage and various ratio parameters correlated significantly with Mini Mental State score, and delta percentage and mean frequency with the lengths of delirium and hospitalisation. The results indicate an association between spectral EEG changes and severity of cognitive deterioration in delirium.
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J. Neurol. Neurosurg. Psychiatr. · Jul 1989
Xanthochromia after subarachnoid haemorrhage needs no revisitation.
Recently it was contended that it is bloodstained cerebrospinal fluid (CSF) that is important in the diagnosis of subarachnoid haemorrhage (SAH) and not xanthochromia, and also that a normal CT scan and the absence of xanthochromia in the CSF do not exclude a ruptured intracranial aneurysm. The CSF findings were therefore reviewed of 111 patients with a proven SAH. All patients had xanthochromia of the CSF. ⋯ All 12 patients survived without disability and were not re-admitted with a SAH (mean follow up 4 years). It is concluded that it is still xanthochromia that is important in the diagnosis of SAH and not bloodstained CSF. Furthermore a normal CT scan and the absence of xanthochromia do exclude a ruptured aneurysm, provided xanthochromia is investigated by spectrophotometry and lumbar puncture is carried out between 12 hours and 2 weeks after the ictus.