Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Apr 2020
Meta AnalysisDifferential response to pallidal deep brain stimulation among monogenic dystonias: systematic review and meta-analysis.
Genetic subtypes of dystonia may respond differentially to deep brain stimulation of the globus pallidus pars interna (GPi DBS). We sought to compare GPi DBS outcomes among the most common monogenic dystonias. ⋯ GPi DBS outcomes vary across monogenic dystonias. These data serve to inform patient selection and prognostic counselling.
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J. Neurol. Neurosurg. Psychiatr. · Mar 2020
Meta AnalysisSleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis.
To conduct an updated systematic review and meta-analysis of association between sleep and all-cause cognitive disorders. ⋯ Sleep management might serve as a promising target for dementia prevention.
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J. Neurol. Neurosurg. Psychiatr. · Jan 2020
Meta AnalysisEfficacy and safety of anti-inflammatory agents for the treatment of major depressive disorder: a systematic review and meta-analysis of randomised controlled trials.
To systematically review the efficacy and safety of anti-inflammatory agents for patients with major depressive disorders. ⋯ Results of this systematic review suggest that anti-inflammatory agents play an antidepressant role in patients with MDD and are reasonably safe.
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J. Neurol. Neurosurg. Psychiatr. · Nov 2019
Meta AnalysisLatitude continues to be significantly associated with the prevalence of multiple sclerosis: an updated meta-analysis.
Previous studies have demonstrated a strong latitudinal gradient in multiple sclerosis (MS) prevalence. Herein, we present a meta-analysis of the latitudinal gradient of MS prevalence including studies published since our 2011 review, seeking to assess the latitudinal gradient and whether it has changed since our previous analysis. ⋯ This new meta-analysis confirms that MS prevalence is still strongly positively associated with increasing latitude and that the gradient is increasing, suggesting that potentially modifiable environmental factors, such as sun exposure, are still strongly associated with MS risk.