JAMA : the journal of the American Medical Association
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Multicenter Study
Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults.
Dietary composition may affect insulin secretion, and high insulin levels, in turn, may increase the risk for cardiovascular disease (CVD). ⋯ Fiber consumption predicted insulin levels, weight gain, and other CVD risk factors more strongly than did total or saturated fat consumption. High-fiber diets may protect against obesity and CVD by lowering insulin levels.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group.
Risedronate, a potent bisphosphonate, has been shown to be effective in the treatment of Paget disease of bone and other metabolic bone diseases but, to our knowledge, it has not been evaluated in the treatment of established postmenopausal osteoporosis. ⋯ These data suggest that risedronate therapy is effective and well tolerated in the treatment of women with established postmenopausal osteoporosis.