Spine
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Multicenter Study
Challenges of local recurrence and cure in low grade malignant tumors of the spine.
Systematic review and ambispective multicenter cohort study. ⋯ When wide or marginal margins (en bloc) are achieved in surgical resection of chordomas and chondrosarcomas of the spine there is a decrease in local recurrence and mortality. Therefore, en bloc resection should be undertaken for the treatment of chordomas and chondrosarcomas of the spine. Strong Recommendation, Moderate Quality Evidence.Radiation therapy of at least 60 to 65 Gy equivalents is indicated as an adjuvant treatment for chordoma and chondrosarcoma of the spine when there has been incomplete resection or an intralesional margin. Weak Recommendation, Low Quality Evidence.
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Randomized Controlled Trial Multicenter Study
The effect of electrical stimulation on lumbar spinal fusion in older patients: a randomized, controlled, multi-center trial: part 2: fusion rates.
Randomized, controlled, multi-center trial. ⋯ Thin slice CT revealed very high nonunion rates after uninstrumented spinal fusion in older patients. DC-stimulation was not effective in increasing fusion rates in this patient population. The achievement of a solid fusion was associated with superior functional outcome.
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Randomized Controlled Trial Multicenter Study Comparative Study
Degenerative spondylolisthesis: does fusion method influence outcome? Four-year results of the spine patient outcomes research trial.
Clinical trial subgroup analysis. ⋯ In patients with DS and associated spinal stenosis, no consistent differences in clinical outcomes were seen among fusion groups over 4 years.