Spine
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Randomized Controlled Trial Comparative Study
A prospective, randomized, blinded, single-site study to evaluate the clinical and radiographic differences between frozen and freeze-dried allograft when used as part of a circumferential anterior lumbar interbody fusion procedure.
Prospective, randomized clinical trial from a single surgeon's patient population. ⋯ When the results are considered in terms of clinical outcomes, the 2 methods of graft preservation perform with few statistically significant differences. Radiographic analysis showed that the freeze-dried graft had a higher likelihood of pseudarthrosis.
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A descriptive cadaveric study. ⋯ The presence of both synoviocytes and chondrocytes has been recorded in the present study, suggesting that the uncovertebral interface is synovial in nature. Immunoreactivity to PGP 9.5, SP, CGRP, and NPY indicates the presence of nerve fibers from both the somatic and autonomic nervous systems. These findings suggest that the uncovertebral joints are potential pain generators in the cervical spine.
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Retrospective case series of magnetic resonance imaging (MRI) findings in patients with presumed infantile idiopathic scoliosis (IIS). ⋯ This study represents the largest evaluation of intraspinal anomalies in IIS to date. Our patient population exhibited a smaller percentage (13%) of neural axis abnormalities than previously reported. On the basis of these findings, the close observation may be a reasonable alternative to an immediate screening MRI in patients presenting with presumed IIS and a curve >20 degrees.
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Prospective study. ⋯ This technique should be recommended because (1) it provides release of anterior column without anterior approach and (2) our results supports its superiority as a technique.
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Biomechanical effect of implantation of an artificial disc (AD) was investigated using the nonlinear three-dimensional finite element model of L4-L5. The SB CHARITE and the Prodisc were chosen as the representative prosthesis of unconstrained and constrained ADs (UADs and CADs) and compared with the intact human intervertebral disc. ⋯ By the result of this study it is obvious that implanted segment with AD has large range of motion and suffers from increased loading to surrounding bone and ligaments. The UAD has larger range of motion but exert less loading to the implanted segment than the CAD. It seems that the mobile center of rotation of the UAD has the ability to lessen the facet contact force and stress on the vertebral body.