Spine
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Intra-arterial injection in the rat brain: evaluation of steroids used for transforaminal epidurals.
Prospective in vivo experimental animal model. ⋯ This study presents the first in vivo evaluation of intra-arterial steroid injection. Data demonstrate Depo-Medrol, as well as its nonparticulate carrier, and Solu-Medrol can produce significant injury to the blood-brain barrier when injected intra-arterially. These results demonstrate that injury is produced not only by particulate obstruction of the cerebral microvasculature, but also by toxicity of the carrier or steroid (methylprednisolone).
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Retrospective cohort. ⋯ Dynamic anterior cervical plating after anterior decompression and grafting provides comparable fusion rates to that reported following the use of rigid cervical plating. Immediate changes in cervical alignment towards lordosis are partially lost on follow-up. The loss of lordosis is related to the amount of graft settling.
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A prospective study. ⋯ For CLBP patients, overall assessment of pain intensity of the day at evening is accurate to assess pain on 1 day. Overall assessment of pain intensity of the day is very close with usual pain. Furthermore, 24 and 48 hours remembered pain intensity are not accurate measures. Recalls of pain on the 7 or 28 last days were very dependant of the pain intensity of the day of the assessment. These findings could contribute to improving pain intensity assessment in CLBP patients avoiding multiple assessments, especially during clinical trials.
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Retrospective functional and radiographic analysis of symptomatic patients with de novo degenerative lumbar and thoracolumbar scoliosis. ⋯ Reduced lumbar lordosis and increased lumbosacral scoliosis can affect the general health status of older patients with de novo degenerative scoliosis. Lateral olisthesis, mainly, and anteroposterior olisthesis are important elements of rotatory subluxation in the lumbar curves, which are important radiographic parameters, predicting symptomatology and health status of patients with de novo degenerative scoliosis.
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Statistical Classification Model for nonspecific chronic low back pain (NS-CLBP) patients and controls based on parameters of motor control. ⋯ Selected biomechanical variables were predictors for subgroup membership and were able to discriminate the 3 subgroups. This study adds further support toward the validation of the proposed classification system.