Spine
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Randomized Controlled Trial
Comparison of 1-Level Versus 2-Level Anterior Cervical Discectomy and Fusion: Clinical and Radiographic Follow-Up at 60 Months.
This study represents a posthoc analysis of data collected from 2 control arms of a prospective, randomized study. ⋯ One- and 2-level ACDF groups improved significantly and maintained improvement throughout 60 month follow-up. When comparing groups, outcomes were often similar, though the 1-level group demonstrated higher fusion rates at 6 and 12 months, greater improvement in NDI scores from 18 to 60-month follow-up, and greater improvement in SF-12 PCS from 12 to 60 months.
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Randomized Controlled Trial
Cognitive Patient Education for Low Back Pain in Primary Care: A Cluster Randomized Controlled Trial and Cost-Effectiveness Analysis.
A pragmatic cluster randomized controlled trial in primary care. ⋯ This study showed no clinical or health economic benefits as a result of adding a cognitive education program to usual treatment for patients with subacute and chronic LBP. Potential weaknesses such as a long recruiting period and potentially low compliance with the cognitive intervention warrant a careful interpretation of the results.
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Randomized Controlled Trial
Body Image and Quality-of-Life in Untreated Versus Brace-Treated Females with Adolescent Idiopathic Scoliosis.
The Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST) included skeletally immature high-risk patients with adolescent idiopathic scoliosis (AIS) with moderate curve sizes (20°- 40°). BrAIST was a multicenter, controlled trial using both randomized and preference treatment arms into either an observation group or a brace treatment group. ⋯ 2.
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Randomized Controlled Trial
Slump Test: Effect of Contralateral Knee Extension on Response Sensations in Asymptomatic Subjects and Cadaver Study.
Part 1: A randomized, single-blind study on the effect of contralateral knee extension on sensations produced by the slump test (ST) in asymptomatic subjects. Part 2: A cadaver study simulating the nerve root behavior of part 1. ⋯ Part 1: In asymptomatic subjects, normal thigh stretch sensations with the ST reduced consistently with the contralateral ST, showing that this is normal and may now be compared with patients with sciatica.Part 2: Contralateral reduction in lumbar neural tension with unilateral application of tension-producing movements also occurred in cadavers, supporting the proposed explanatory hypothesis.
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Randomized Controlled Trial
Five-year Follow-up of a Prospective, Randomized Trial Comparing Two Lumbar Total Disc Replacements.
This was a prospective, randomized, controlled, multicenter study. ⋯ This prospective, randomized study comparing two TDRs found no significant differences in outcomes during 5-year follow-up. Both provided statistically significant improvements by 6 weeks that were maintained. This results support other studies. Serum ion levels in TDR patients were well below the recommended threshold levels to merit monitoring.