Preventive medicine
-
Preventive medicine · Aug 2023
A novel protective role of lipoxin in inhibiting diabetic vascular calcification via YAP signalling: Health prevention and regulation.
Vascular calcification is highly prevalent in diabetes patients, with detrimental consequences and no effective prevention and treatment strategies are currently available. Though the protective effect of lipoxin (LX) against vascular diseases has been demonstrated, its effect on diabetic vascular calcification remains unknown. AGEs dose-dependently induced calcification and the expression of osteogenesis-related markers, coupled with the activation of yes-associated protein (YAP). ⋯ Further, an in vivo diabetic mouse model was established using a combination of a high-fat diet and multiple formulations of low-dose streptozotocin. Consistent with the in vitro results, diabetes promoted YAP expression and its subcellular localization in the nucleus in the arterial tunica media. The results demonstrate that LX attenuates the trans-differentiation and calcification of VSMCs in diabetes mellitus via YAP signalling, suggesting LX to be a potent therapeutic for preventing diabetic vascular calcification.
-
Preventive medicine · Aug 2023
Simulation of sports training recognition system based on internet of things video behavior analysis.
The video behavior analysis of the Internet of Things is the apparent characteristics and continuous state of the two-dimensional human body in the time dimension. The patterns representing human behavior can be divided into states based on human body structure, forms based on common features and forms based on temporal features, local spaces, and behaviors based on deep learning. Applying IoT video behavior analysis to sports training will have a huge impact. ⋯ This method can accurately meet the low-delay requirements of the motion recognition of each frame and the standard motion. It can match and eliminate the influence of individual differences on motion recognition. At the same time, it can also effectively expand the pattern matching method to recognize newly filled motions, and it is a powerful composite general motion recognition system.
-
Preventive medicine · Aug 2023
Work-life interference and health by race/ethnicity and sex in the United States.
Work-life interference has detrimental impacts on health outcomes. However, there are potential differences in these associations at the intersection of race/ethnicity and sex. The aim of this study was to examine whether race/ethnicity moderates the associations of work-life interference with health outcomes among women and men. ⋯ The results suggest detrimental impacts of work-life interference on self-rated health and psychological distress. Yet, the variation in the associations of work-life interference with psychological distress and BMI among women suggest that an intersectional lens should be applied. Efforts to understand and address the negative effects of work-life interference on health should consider potentially unique associations across race/ethnicity and sex.
-
Preventive medicine · Aug 2023
Public risk perception of air pollution in the general population of Italy and Sweden during the COVID-19 pandemic: Environmental and socio-demographic drivers.
Air pollution is an important anthropogenic hazard due to its effect on human health and the environment. Understanding how the population perceives the risk associated with air pollution is a crucial aspect to inform future policies and communication strategies. The aim of this study is to examine the association between air pollution concentrations and public risk perception of air pollution, also exploring socio-demographic patterns in the general population of Italy and Sweden. ⋯ Direct experience is the main driver of risk perception in both countries. Being male and smokers in Italy, older age and having left/centre-left political orientation in both countries are associated with a higher perceived likelihood and impact of air pollution. These findings will inform future health and environmental studies regarding the public risk perception of air pollution highlighting individual's awareness and the socio-demographic patterns.
-
Accumulating evidence suggests that the built environment may be associated with cardiovascular disease via its influence on health behaviours. The aim of this study was to estimate the associations between traditional and novel neighbourhood built environment metrics and clinically assessed cardio-metabolic risk factors among a sample of adults in Canada. A total of 7171 participants from Albertas Tomorrow Project living in Alberta, Canada, were included. ⋯ Space syntax walkability was also associated with lower odds of overweight/obese among women and men (OR = 0.93, 95% CI 0.87, 0.99 and OR = 0.88, 95% CI 0.79, 0.97, respectively). No significant associations were observed between traditional walkability and cardio-metabolic outcomes. This study showed that the novel built environment metric based on the space syntax theory was associated with some cardio-metabolic risk factors.