The American journal of emergency medicine
-
Meta Analysis
Significant association between anemia and higher risk for COVID-19 mortality: A meta-analysis of adjusted effect estimates.
This study aimed to evaluate whether there was a significant relationship between anemia and the risk for mortality among coronavirus disease 2019 (COVID-19) patients by a quantitative meta-analysis based on the adjusted effect estimates. ⋯ Our meta-analysis based on risk factors-adjusted effect estimates indicated that anemia was independently associated with a significantly elevated risk for mortality among COVID-19 patients.
-
Buprenorphine precipitated opioid withdrawal (BPOW) is an uncommon complication of buprenorphine initiation in the emergency department (ED), but it can produce significant discomfort and be distressing to patients. As EDs continue to care for those with opioid use disorder (OUD), clinicians should be aware of how to prevent and treat BPOW. ⋯ Appropriate initiation of buprenorphine is important to prevent BPOW. Dosing buprenorphine should be based on the patient's patterns of opioid use and response to therapy. Management of BPOW should be symptom-based but include additional buprenorphine and adjunctive medications.
-
Review Comparative Study
Comparison of tenecteplase versus alteplase in STEMI patients treated with ticagrelor: A cross-sectional study.
The effectiveness and safety of administration of ticagrelor simultaneously with fibrinolytic agents in STEMI patients remain unclear. ⋯ The administration of tenecteplase in STEMI patients who received a loading dose with ticagrelor resulted in a significant reduction in MACE compared to alteplase. Larger multi-center studies are warranted to investigate the effect of tenecteplase treatment on clinical results.
-
Right heart failure (RHF) is a clinical syndrome with impaired right ventricular cardiac output due to a variety of etiologies including ischemia, elevated pulmonary arterial pressure, or volume overload. Emergency department (ED) patients with an acute RHF exacerbation can be diagnostically and therapeutically challenging to manage. ⋯ Emergency clinician understanding of this condition is important to diagnose and treat this life-threatening cardiopulmonary disorder.
-
Meta Analysis
Effectiveness of yoga therapy for migraine treatment: A meta-analysis of randomized controlled studies.
Yoga therapy may have some potential in treating migraine, and thus this meta-analysis aims to explore the efficacy of yoga therapy for patients with migraine. ⋯ Yoga therapy may be effective to treat migraine patients, but it should be recommended with caution because of heterogeneity.