Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Case Reports
Potential role of PMD-TCD monitoring in the management of hemodynamically unstable intracranial stenosis.
A 54-year-old woman started to loose vision 2 days prior to admission and also experienced left-sided headache, nausea, emesis, and disorientation. Magnetic resonance imaging (MRI) revealed bilateral posterior cerebral artery and cerebellar infarctions. Transcranial power motion Doppler (PMD-TCD) showed blunted flow signal in the proximal basilar artery (BA) suggestive for a high-grade stenosis also seen on magnetic resonance angiography (MRA). ⋯ PMD-TCD findings were suggestive for an intraluminal thrombus that moved from the proximal to the distal basilar artery, presumably further contributing to brain stem hypoperfusion and neurological deterioration. To achieve a compromise between lower blood pressure and maintenance of brain perfusion, hypervolemic hemodilution with intravenous dextran-40 was initiated. Patient's symptoms resolved to baseline and MRI showed no new parenchymal lesions.
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We aimed to determine the displacement parameters in the brains of normal individuals relative to brain parenchymal abnormalities, such as multiple sclerosis (MS) and low-grade glioma, by q-space imaging (QSI) using 1.5-T magnetic resonance (MR) scanner. ⋯ We propose that the relative values of MD obtained by QSI in control and diseased tissues can be useful for diagnosing various WM abnormalities.
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We attempt to evaluate objectively the regional cerebral blood flow (rCBF) changes during long-term donepezil therapy and the relationship between the clinical response and rCBF change in patients with Alzheimer's disease (AD). ⋯ The progression of cognitive deterioration may be related to rCBF affected by the neuropathologic changes of AD.
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To determine the proper method for the normalization of spinal cord volume. ⋯ Since normalization factor had limited impact on reliability and the ability to detect differences, normalization by the number of slices is recommended.