International journal of clinical practice
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Int. J. Clin. Pract. · Sep 2021
Meta AnalysisThe effect of soy products on circulating adiponectin and leptin concentration in adults: A systematic review and meta-analysis of randomized controlled trials.
Human clinical trials that have investigated the effect of soy product consumption on adipokines have reported inconsistent results. Our objective was to elucidate the role of soy product consumption on adiponectin and leptin in adults through a systematic review and meta-analysis of available randomised placebo-controlled trials (RCTs). ⋯ The present systematic review and meta-analysis suggest that soy product consumption had no significant effect on leptin and adiponectin levels in adults. However, future larger and well-designed trials are still needed to further explore this research area and to address the heterogeneous study design used in the existing literature.