International journal of clinical practice
-
Int. J. Clin. Pract. · Sep 2021
Randomized Controlled Trial Comparative StudyComparison of Transcutaneous Tibial Nerve Stimulation (TTNS) Protocols for Women with Refractory Overactive Bladder (OAB): a Prospective Randomized Trial.
Transcutaneous tibial nerve stimulation (TTNS) is a noninvasive method used in OAB treatment. Purpose of this study is to compare the effectiveness of the TTNS procedure applied once a week and three times a week in women diagnosed with wet type refractory OAB. ⋯ TTNS can be safely used before invasive treatments in resistant OAB. TTNS procedure three times a week seems more effective than performing it once a week. What's known TTNS is one of the effective alternative treatments in resistant OAB treatment. What's new As the number of sessions is increased in TTNS treatment, the success of the treatment can increase.
-
Int. J. Clin. Pract. · Sep 2021
Randomized Controlled TrialEfficacy and safety of ultrasound-guided quadratus lumborum block in patients receiving percutaneous nephrolithotomy under general anesthesia.
The aim of this study was to explore the overall efficacy and safety of ultrasound-guided quadratus lumborum block combined with general anaesthesia in patients undergoing percutaneous nephrolithotomy (PCNL). ⋯ The combination of ultrasound-guided quadratus lumborum block and general anaesthesia effectively exerts beneficial outcomes in terms of validly reducing the dose of tranquilisers and anaesthetic analgesics during PCNL, which is able to treat patients with anaesthetic mode of low opioids.
-
Int. J. Clin. Pract. · Sep 2021
Randomized Controlled TrialComparison of serum dynamic thiol/disulfide homeostasis and nitric oxide levels of total intravenous versus inhaled anesthesia in endoscopic transsphenoidal pituitary surgery.
Transsphenoidal pituitary surgery (TPS) is traditionally performed under general anaesthesia. This study aimed to compare the effects of total intravenous anaesthesia (TIVA) or sevoflurane, an inhalation anaesthetic, on thiol-disulphide homeostasis in patients undergoing endoscopic endonasal TPS. ⋯ These results are the first to show that both TIVA and sevoflurane showed similar antioxidant effect with reduced disulphide levels, but sevoflurane may offer more robust oxidative stress protection and augmented NO production than TIVA during TPS. However, the clinical effect is needed to further investigate.
-
Int. J. Clin. Pract. · Sep 2021
Randomized Controlled TrialThe efficacy of Alpha-Lipoic Acid in improving oxidative, inflammatory and mood status in women with episodic migraine in a randomized, double-blind, placebo-controlled clinical trial.
Migraine is a common neurovascular disorder, which is associated with severe to moderate disabling headaches. Oxidative stress and inflammation might play a role in migraine pathogenesis and the mood disorders. Considering the antioxidant and anti-inflammatory properties of alpha-lipoic acid (ALA), this study was designed to investigate its effect on oxidative, inflammatory, and mood conditions in women with episodic migraine. ⋯ The results of this study suggest that ALA supplementation for 3 months has beneficial effects on improving the oxidative, inflammatory, and mood conditions of patients suffering from episodic migraine.
-
Int. J. Clin. Pract. · Sep 2021
Randomized Controlled TrialEfficacy of cranial microcurrent stimulation in patients with tension-type headache: A prospective, randomized, double-blinded, sham-controlled clinical trial.
To investigate the therapeutic effect of cranial microcurrent stimulation (CMS) in patients with tension-type headaches (TTH). ⋯ The results indicate that CMS, as an adjunctive treatment for patients with TTH, is safe and analgesic as well as reducing depression or anxiety.