Turk J Gastroenterol
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Turk J Gastroenterol · May 2019
Meta AnalysisStandard triple therapy in Helicobacter pylori eradication in Turkey: Systematic evaluation and meta-analysis of 10-year studies.
This study aims at evaluating the mean eradication rate by a systematic compilation of the studies which involved the standard triple therapy (STT) in first-line Helicobacter pylori (Hp) eradication in Turkey over a period of 10 years between 2004 and 2013 using the meta-analysis method. ⋯ A systematic meta-analysis of studies conducted during the period 2004-2013 in Turkey revealed that the rate of first-line Hp eradication using STT was unacceptably low, and the duration of treatment and PPI used made no difference.
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Turk J Gastroenterol · Oct 2011
Meta AnalysisEfficacy evaluation of imatinib in the treatment of patients with gastrointestinal stromal tumors.
Published data on the dose of imatinib to treat gastrointestinal stromal tumors seemed inconclusive. To derive a more precise estimation of dose of imatinib to treat gastrointestinal stromal tumors, a meta-analysis was performed. ⋯ The meta-analysis indicated that cumulative response for patients with low-dose imatinib showed no significant difference compared with that with high-dose imatinib. However, high-dose imatinib brought patients more toxic effect and more dosage adjustment for down regulation was made for these patients with severe toxic effect. With long follow-up of the patients, result of neither progression-free survival nor overall survival reached statistical significance between low-dose arm and high-dose arm.