Revista española de anestesiología y reanimación
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Rev Esp Anestesiol Reanim · May 1994
Randomized Controlled Trial Comparative Study Clinical Trial[Comparison between fentanyl and a fentanyl-bupivacaine combination using epidural PCA for postoperative analgesia after thoracotomy].
The association of opioids and local anesthetics for spinal analgesia appears to have a synergistic++ effect. ⋯ The analgesic effect obtained with epidural fentanyl or fentanyl/bupivacaine is similar and adequate, and the association of fentanyl and bupivacaine can be considered safe.
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Rev Esp Anestesiol Reanim · May 1994
Randomized Controlled Trial Comparative Study Clinical Trial[Does propofol have advantages over midazolam and isoflurane? Comparative study of 2 total intravenous anesthesia techniques using midazolam and propofol, versus balanced anesthesia with isoflurane].
To compare two techniques for total intravenous anesthesia (TIVA): midazolam-alfentanil-flumazenil and propofol-alfentanil, contrasting them with combined anesthesia (thiopental-isoflurane-alfentanil) and assessing the efficacy of flumazenil in continuous perfusion for preventing resedation in TIVA with midazolam. ⋯ None of the TIVA techniques proved superior in all the parameters studied during anesthetic maintenance when compared with balanced isoflurane-alfentanil, although the propofol-alfentanil combination was found to be superior to that of midazolam-alfentanil. After anesthesia, however, recovery was better with the association of propofol-alfentanil and adverse side effects were fewer. Flumazenil at the doses used was ineffective for preventing resedation due to midazolam.
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Rev Esp Anestesiol Reanim · Mar 1994
Randomized Controlled Trial Comparative Study Clinical Trial[Comparative study between anesthesia by continuous perfusion with propofol or thiopental-isoflurane in laryngeal surgery].
To compare two anesthetic protocols for maintenance of anesthesia during laryngectomy (propofol vs thiopental-isoflurane), assessing its effects on intraoperative hemodynamic stability and recovery time after withdrawal of anesthesia. ⋯ Propofol for anesthetic maintenance is effective and safe. There are no differences in hemodynamic changes produced by propofol and isoflurane. Time until recovery of consciousness is longer with isoflurane, although we believe that this is not clinically relevant in this type of procedure.
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Rev Esp Anestesiol Reanim · Mar 1994
Randomized Controlled Trial Comparative Study Clinical Trial[Premedication with clonidine in the neurosurgical patient: sedation, anesthetic requirements and hemodynamic perfusion].
To analyze the effect of premedication with clonidine on postoperative sedation, anesthetic requirements and hemodynamic repercussions in patients undergoing craniotomy due to supratentorial intracranial pathology. ⋯ Premedication of neurosurgical patients with clonidine offers no advantages over lorazepam with respect to sedation. Nevertheless, clonidine may offer advantages with respect to the amount of alfentanyl required and attenuation of perioperative adrenergic response.
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Rev Esp Anestesiol Reanim · Mar 1994
Comment Randomized Controlled Trial Comparative Study Clinical Trial[Oral premedication with clonidine in patients undergoing coronary revascularization surgery].
To analyze the effect of premedication with clonidine on level of sedation, anesthetic requirements and hemodynamic repercussions in patients undergoing coronary revascularization. ⋯ Use of clonidine in the type of patient studied does not improve the level of sedation over that achieved with lorazepam. Fentanyl requirements decreased with clonidine. With respect to hemodynamic profile, systemic vascular resistance fell in the clonidine group after removal of ECC, and thus this drug offers no advantages for routine premedication.