Revista española de anestesiología y reanimación
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Rev Esp Anestesiol Reanim · May 1993
Randomized Controlled Trial Clinical Trial[Thoracic paravertebral blockade: postoperative analgesic effectiveness and plasma concentrations of bupivacaine].
To compare the analgesic efficacy of thoracic paravertebral blockade with that of endovenous morphine to measure the plasma levels of bupivacaine and to study the complications derived from both techniques in patients undergoing thoracic or abdominal surgery with unilateral incision. ⋯ Thoracic paravertebral blockade is a very effective postoperative analgesic technique and is superior to that of i.v. morphine in patients undergoing thoracic or unilateral abdominal surgery. Peak plasma levels were much lower than those considered as toxic complications of interest were observed. Therefore, this technique may be considered as an alternative to other blockades such as extradural, interpleural or intercostal.
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Rev Esp Anestesiol Reanim · May 1993
Randomized Controlled Trial Comparative Study Clinical Trial[Intubation with propofol without neuromuscular blockade. Effect of premedication on fentanyl and lidocaine].
Laryngotracheal reflexes, and possibilities of intubations following anaesthetic induction with propofol, with or without premedication and without neuromuscular blockade were evaluated. Hemodynamic parameters were also measured. ⋯ The use of propofol without neuromuscular blockade is inadequate for intubation since laryngotracheal reflexes are not suppressed. Besides, propofol does not prevent hemodynamic reactions. Premedication with fentanyl and/or lidocaine improves the responses not sufficiently to safely perform intubation.
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Rev Esp Anestesiol Reanim · Nov 1992
Letter Randomized Controlled Trial Clinical Trial[Cryoanalgesia in post-thoracotomy pain].
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Rev Esp Anestesiol Reanim · Sep 1992
Randomized Controlled Trial Clinical Trial[Efficacy of topical administration of lidocaine through a Malinckrodt Hi-Lo Jet tube in lessening cough during recovery from general anesthesia].
To achieve tracheal anesthesia during intubation, an endotracheal tube was purposely designed. The tube had multiple laser-induced perforations in its lower portion produced that allowed administration of the local anesthetic in a pulverized form. We evaluated the efficacy of lidocaine 2% in preventing cough during recovery from general anesthesia. ⋯ At the end of the anesthesia period, the presence of cough was treated with the test solution. In 90% of cases treated with lidocaine, cough disappeared in about 30 seconds and patients tolerated the endotracheal tube until extubation was performed. All patients who received saline solution presented cough until extubation.
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Rev Esp Anestesiol Reanim · May 1992
Randomized Controlled Trial Clinical Trial[Changes in plasma cortisol and ACTH caused by diazepam, bromazepam, triazolam, and alprazolam in oral premedication].
Benzodiazepines relieve anxiety and modify the endocrine response to surgical-anesthetic stress. ⋯ Benzodiazepines failed to modify cortisol and ACTH levels during surgery and during the immediate postoperative period. The most marked attenuation of adrenocortical response was achieved with 12 mg of bromazepam and the less marked lessening was induced by 0.5 mg of alprazolam.