Zhonghua wei zhong bing ji jiu yi xue
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2017
Review[Severe disease of immune imbalance in ICU: persistent inflammation immunosuppression catabolism syndrome].
Terminology of persistent inflammation immunosuppression and catabolism syndrome (PICS) is developed based on the concept of multiple organ failure (MOF), which reflect that the preponderance is gradually reversed from pro-inflammation to anti-inflammation, and eventually the state of simultaneously persistent inflammation and severe immunosuppression appeared. Although the improvement of rescue technology and management increase the early survival rates of patient with critical illnesses, the long-term outcomes of most patients are not optimistic. The patients with PICS are difficult to treat or prevent, and are likely to indolent death and have a rising incidence, which is an important challenge to the intensive care unit (ICU). The paper review the understanding of PICS, summarize the specific changes of immune system in PICS, and explore the immunological markers for early recognition of PICS and judgment of immune state in order to provide new thinking for prevention and control of PICS.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2017
Review[Research advances of the role of inflammatory responses in ARDS].
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is an inflammatory lung injury induced by a variety of factors, and these diseases are associated with high rates of mortality due to the lack of effective treatments. Based on the latest research in ALI/ARDS, it is widely accepted that generalized inflammatory responses play a critical role in initiating and developing process of ALI/ARDS. We make a brief review on the immune-pathogenesis and the signaling pathways of ALI/ARDS from the perspective of inflammation, thereby helping develop novel therapeutic strategy for treatment of patients with ALI/ARDS.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2017
[Ventilator bundle guided by context of JCI settings can effectively reduce the morbidity of ventilator-associated pneumonia].
To observe the impact of improving the compliance of ventilator bundle on morbidity of ventilator-associated pneumonia (VAP) in intensive care unit (ICU) patients undergoing mechanical ventilation (MV) guided by context of Joint Commission International (JCI) settings, and to study the oral care efficacy of suction tube sponge brush. ⋯ Ventilator bundle can effectively reduce the morbidity of VAP in the context of JCI settings, and the oral care by using suction tube sponge brush and chlorhexidine can effectively improve oral hygiene.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2017
[Analysis of factors affecting the prognosis of ICU patients by multiple logistic regression model: a retrospective cohort study of 1 299 patients in 12 consecutive years].
To explore the prognostic factors of intensive care unit (ICU) patients. ⋯ Whether the success of weaning, whether the occurrence of AKI or septic shock are independent prognostic factors for the prognosis of ICU patients. Measures for the prevention of the above three aspects could improve the prognosis of ICU patients.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2017
Randomized Controlled Trial[Effect of external abdominal aorta compression on circulation during anesthesia induction in elderly patients].
To investigate the effect of external abdominal aorta compression on circulation during anesthetic induction in elderly patients. ⋯ Anesthesia induction of elderly patients with abdominal aorta pressure can help maintain hemodynamic stability.