Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Oct 2007
Randomized Controlled Trial[Effect of different tidal volume ventilations on atelectasis in patients during general anesthesia by CT scan].
To investigate the effect of different tidal volume ventilations on the amount of atelectasis during general anesthesia. ⋯ Low tidal volume(6 mL/kg) ventilation is more feasible during general anesthesia in patients with healthy lungs, and it does not increase the atelectasis and impairment of gas exchange.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Oct 2007
[Effect of rosiglitazone on NO and eNOS via PI3K/PKB signal pathways in cultured human umbilical vein endothelial cells].
To observe the effect of rosiglitazone on the production of nitric oxide (NO) and the expression of phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) /the endothelial nitric oxide synthase (eNOS) in cultured human umbilical vein endothelial cells(HUVECs), and to investigate the mechanism of signal transduction of rosiglitazone in improving the endothelial function. ⋯ Treatment with rosiglitazone can increase the NO production and improve the endothelial function through up-regulating the PI3K/PKB/eNOS signal pathways in cultured HUVECs.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Aug 2007
Randomized Controlled Trial[Effect of mechanical ventilation with different tidal volumes on the respiratory function during general anesthesia].
To determine the effect of mechanical ventilation with different tidal volumes on the respiratory function during general anesthesia and to seek optimum way and parameters of mechanical ventilation during general anesthesia. ⋯ The optimum tidal volume of mechanical ventilation is not 4 mL/kg at the rate of 15 respiratory rate during general anesthesia in the supine position because of a high arterial carbon dioxide tension. Yet 6-8 mL/kg is better for neurosurgical anesthesia. Increasing the tidal volume alone may not improve the respiratory function impairment during general anesthesia.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Aug 2007
[Intrathecal injection of ketamine and clonidine for chronic neuropathic pain model in rats].
To observe the effect of intrathecal injection of ketamine and clonidine for chronic constriction injury (CCI) in rats. ⋯ The combined injection of ketamine and clonidine can produce synergistic ab-irritation without obvious side effects.
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Zhong Nan Da Xue Xue Bao Yi Xue Ban · Jun 2007
Multicenter Study[Sevoflurane used for induction and maintenance of anaesthesia in children].
To observe the effect of sevoflurane on the induction and maintenance of anaesthesia in children, and to evaluate its safety and effectiveness. ⋯ Sevoflurane for children induction can bring fewer stimuli in the respiratory tract,less cardiac vascular inhibition and palinesthesia time. Anaesthesia in children induced by sevoflurane is safe and effective.