Articles: adult.
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Review Meta Analysis
Optimal wrist positioning for radial arterial cannulation in adults: A systematic review and meta-analysis.
Wrist extension is commonly taught as part of the radial artery cannulation technique. Currently the degree of wrist extension required to optimize cannulation success remains inconclusive. This is the first meta-analysis to investigate optimal wrist positioning for radial artery cannulation. ⋯ This review found moderate evidence in support of a 45° wrist angulation to facilitate arterial cannulation, however the results are largely limited by the external validity of the data collected given the restrictive populations studied. Any further studies investigating the effect of altering wrist angulation on radial artery cannulation should focus on populations who are either likely to require arterial cannulation or predisposed to difficult access.
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Review Meta Analysis
Statins for Prevention of Cardiovascular Disease in Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force.
Cardiovascular disease (CVD), the leading cause of mortality and morbidity in the United States, may be potentially preventable with statin therapy. ⋯ In adults at increased CVD risk but without prior CVD events, statin therapy was associated with reduced risk of all-cause and cardiovascular mortality and CVD events, with greater absolute benefits in patients at greater baseline risk.
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Acta Anaesthesiol Scand · Oct 2016
Review Meta AnalysisGabapentin for post-operative pain management - a systematic review with meta-analyses and trial sequential analyses.
Perioperative pain treatment often consist of combinations of non-opioid and opioid analgesics, 'multimodal analgesia', in which gabapentin is currently used. The aim was to document beneficial and harmful effects of perioperative gabapentin treatment. ⋯ Based on GRADE assessment of the primary outcomes in trials with low risk of bias, the results are low or very low quality of evidence due to imprecision, inconsistency, and in some outcomes indirectness. Firm evidence for use of gabapentin is lacking as clinically relevant beneficial effect of gabapentin may be absent and harm is imminent, especially when added to multimodal analgesia.
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Review Meta Analysis
Direct Bypass versus Indirect Bypass in Adult Moyamoya Angiopathy with Symptoms or Hemodynamic Instability: a Meta-analysis of Comparative Studies.
It remains controversial which bypass methods are optimal for treating adult moyamoya angiopathy patients. This study aimed to analyze the literature about whether different bypass methods affect differently outcome results of adult moyamoya patients with symptoms or hemodynamic instability. ⋯ The current meta-analysis suggests that the direct or combined bypass surgical method is better for angiographic revascularization in adult moyamoya patients with symptoms or hemodynamic instability. Future studies may be necessary to confirm these findings.
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Review Meta Analysis
First do no harm: pain relief for the peripheral venous cannulation of adults, a systematic review and network meta-analysis.
Peripheral venous cannulation is an everyday practice in hospitals, which many adults find painful. However, anaesthesia for cannulation is usually only offered to children. Inadequate pain relief is not only unpleasant for patients but may cause anxiety about further treatment and deter patients from seeking medical care in the future. The aim of this study is to discover the most effective local anaesthetic for adult peripheral venous cannulation and to find out how the pain of local anaesthetic application compares with that of unattenuated cannulation. ⋯ The protocol for the larger study was registered with PROSPERO no. CRD42012002093 .