Articles: pediatrics.
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Pediatric emergency care · Feb 2015
Meta AnalysisThe Efficacy of Isotonic and Hypotonic Intravenous Maintenance Fluid for Pediatric Patients: A Meta-analysis of Randomized Controlled Trials.
This study aimed to analyze the effect of isotonic versus hypotonic solution as intravenous maintenance fluid on level of plasma sodium in hospitalized children. ⋯ The meta-analysis revealed that there was potential risk of hyponatremia for routine infusion of hypotonic maintenance fluid. The use of isotonic solution was warranted in hospitalized pediatric patients.
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Paediatric anaesthesia · Feb 2015
Review Meta AnalysisSystematic Review and Meta-Analysis of benefits and risks between normothermia and hypothermia during cardiopulmonary bypass in pediatric cardiac surgery.
The controversy over the benefits between normothermic and hypothermic cardiopulmonary bypass (CPB) for children is still uncertain. The purpose of this systematic review and meta-analysis is to investigate the benefits and risks of normothermia comparing with hypothermia in pediatric cardiac surgery by randomized controlled trials. ⋯ Normothermic CPB is as safe as hypothermic CPB in children requiring correction of simple congenital cardiac defects.
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Review Meta Analysis
Immediate Rescue Designs in Pediatric Analgesic Trials: A Systematic Review and Meta-analysis.
Opioid sparing is a feasible pragmatic endpoint for pediatric pain analgesic trials.
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Int J Clin Exp Patho · Jan 2015
Review Meta AnalysisEpsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials.
Excessive postoperative blood loss after cardiopulmonary bypass is a common problem, especially in patients suffering from congenital heart diseases. The efficacy of epsilon aminocaproic acid (EACA) as a prophylactic treatment for postoperative bleeding after pediatric open-heart surgery has not been determined. This meta-analysis investigates the efficacy of EACA in the minimization of bleeding and blood transfusion and the maintenance of coagulation tests after pediatric open-heart surgery. ⋯ Prophylactic EACA minimizes postoperative blood transfusion and helps maintain coagulation in pediatric patients undergoing open-heart surgery. Therefore, the results of this study indicate that adjunctive EACA is a good choice for the prevention of postoperative blood transfusion following pediatric cardiac surgery.
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Review Meta Analysis
The relationship between migraine and infant colic: a systematic review and meta-analysis.
Infant colic is a common and distressing disorder of early infancy. Its etiology is unknown, making treatment challenging. Several articles have suggested a link to migraine. ⋯ In this meta-analysis, infant colic was associated with increased odds of migraine. If infant colic is a migrainous disorder, this would have important implications for treatment. The main limitation of this meta-analysis was the relatively small number of studies included.