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Currently, survival from out-of-hospital cardiac arrest in the United Kingdom is poor. Ambulance response standards require that an ambulance reach 75 per cent of cardiac arrests within 8 min. But a short time to defibrillation from the onset of collapse is a key predictor of outcome from out-of-hospital cardiac arrest. ⋯ It has been calculated that there are approximately 5,000 instances of VF in public places each year in England. If half of these patients can be reached and administered a first shock within 4 min of their collapse, an additional 400 victims may survive each year. Given the current investment by the DoH of 2 million pounds, this suggests a cost per life saved of approximately 505 pounds over a 10 year period.
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Inhalation of a foreign body into the respiratory passage can be a serious and sometimes fatal childhood accident. In this paper we analyse the management of 223 children with laryngo-tracheo-bronchial foreign bodies. Children below three years of age were found to be the most vulnerable. ⋯ In one hundred and five (47.1 per cent) the objects found their way into the right bronchial tree. There were two deaths. The modalities of diagnosis and management are discussed.
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Expert Opin Drug Saf · Nov 2005
ReviewThe safety and efficacy of the use of vasopressin in sepsis and septic shock.
Sepsis remains a significant problem and cause of morbidity and mortality in intensive care. Vasopressin infusions are currently used as rescue therapy for the treatment of vasodilatory, catecholamine-resistant septic shock. ⋯ A review of the safety data for vasopressin in this indication is included. Recommendations for the use of vasopressin in septic shock, along with suggestions for the direction of further work in the field are presented.