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Dtsch. Med. Wochenschr. · Mar 2001
Review Comparative Study[Mental disorders and criminal violence: myths and facts].
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Remifentanil is a 4-anilidopiperidine mu-opioid analgesic which is rapidly metabolized by unspecific blood and tissue esterases. According to its unique pharmacokinetic profile, remifentanil-based anaesthesia combines high-dosage opioid analgesia intraoperatively with a rapid and predictable postoperative awakening. ⋯ The present paper was designed to review the current knowledge on remifentanil and all aspects of its use in anaesthesiology. In addition, present data on the use of remifentanil for analgesia and sedation of the critically ill patient are summarized.
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Nicotine dependence is a significant addiction with many health consequences. Consistent attempts and efforts at addressing this condition, guiding and advising afflicted patients using motivational techniques and the 5-A stepwise strategies, and instituting appropriate therapies will result in better health outcomes and less incidence of diseases. In pharmacotherapy, Nicotine replacement therapy and oral medications can be used alone or in combination with varying degrees of success.
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The term subclinical thyroid disorders apply to patients who have an abnormal serum thyroid-stimulating hormone (TSH) concentration but thyroxine and triiodothyronine levels within their reference ranges. Subclinical hypothyroidism occurs in 4% to 10% of the general population, and is especially prevalent in elderly women. Depending on the study, subclinical hyperthyroidism has been found in 0.6-16 % of the population. ⋯ Treatment of subclinical thyroid disorders is controversial. In this paper, we discuss the prevalence, aetiology, clinical presentation, diagnosis, natural history, and potential pathophysiological consequences of subclinical hypothyroidism and subclinical hyperthyroidism. We also provide some screening and management recommendations.