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Multicenter Study
Blood transfusion increases the risk of infection after trauma.
To determine whether blood transfusion influences infection after trauma, we analyzed data on 5366 consecutive patients hospitalized for more than 2 days at eight hospitals over a 2-year period. The incidence of infection was significantly related to the mechanism of injury: penetrating injuries, 8.9%; blunt injuries, 12.9%; and low falls, 21.4%. ⋯ Blood transfusion in the injured patients is an important independent statistical predictor of infection. Its contribution cannot be attributed to age, sex, or the underlying mechanism of severity of injury.
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Drug and alcohol review · Jan 2015
Multicenter StudyType of opioids injected: does it matter? A multicentric cross-sectional study of people who inject drugs.
Injecting pharmaceutical opioids for non-medical purposes is a major concern globally. Though pharmaceutical opioids injection is reported in India, the exact proportion of people who inject drugs (PWID) using pharmaceutical opioids is unknown. The objectives of this study were to describe the various types of drugs that are injected by people in India and to analyse the differences between the commonly injected drugs. ⋯ Pharmaceutical opioids are the most common drugs injected in India currently and have greater injection-related risks and complications. Significant differences exist between different pharmaceutical opioids, which would be important considerations for interventions.
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Multicenter Study
[Skills and requirements of residents. Teaching resources to help tutors in a situation of change].
To determine indicators of the skills and expectations of family and community medicine (FMC) residents (MIR). To construct teaching resources to value skills and expectations individually and continuously. ⋯ The skills and requirements of both tutors and residents need to be known, if training is to be in the interests of both. This study contributes instruments that aid teaching work and an opportunity for collaboration by gathering questions that concern tutors.
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Randomized Controlled Trial Multicenter Study Comparative Study
5-year results of accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy versus whole-breast irradiation with boost after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: a randomised, phase 3, non-inferiority trial.
In a phase 3, randomised, non-inferiority trial, accelerated partial breast irradiation (APBI) for patients with stage 0, I, and IIA breast cancer who underwent breast-conserving treatment was compared with whole-breast irradiation. Here, we present 5-year follow-up results. ⋯ German Cancer Aid.
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Multicenter Study
Risk and protective factors for falls on stairs in young children: multicentre case-control study.
To investigate risk and protective factors for stair falls in children aged <5 years. ⋯ Structural factors including having landings part-way up the stairs and keeping stairs in good repair were associated with reduced stair fall injury risk. Family factors including having stair gates, not leaving gates open and having stair carpets were associated with reduced injury risk. If these associations are causal, addressing these factors in housing policy and routine child health promotion could reduce stair fall injuries.