• metajournal
  • Join

    metajournal

    21 day free trial
    Articles. Pearls. Topics. Reviews. Journal Clubs.
    Stay informed.
  • Sign in
  • About
  • Pricing
  • Help
  • Blog
  • Articles
  • Knowledge
  • Topics
  • Notes



  • Is nitrous oxide use safe in anesthesia?

    Collection
     
    • Randomized Controlled Trial

      The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial.

      Lancet. 2014 Oct 18;384(9952):1446-54.

      Nitrous oxide use in non-cardiac surgery does not increase the risk of death, cardiovascular complications or wound infection.

      pearl
    • Randomized Controlled Trial

      Leukocyte DNA damage and wound infection after nitrous oxide administration: a randomized controlled trial.

      Anesthesiology. 2013 Jun 1;118(6):1322-31.

      Nitrous oxide exposure increases DNA damage which may be associated with increased risk of wound infection after colorectal surgery.

      pearl
    • Review

      Does anaesthesia with nitrous oxide affect mortality or cardiovascular morbidity? A systematic review with meta-analysis and trial sequential analysis.

      Br J Anaesth. 2014 Mar 1;112(3):410-26.

      Available evidence does not support the claim that nitrous oxide affects mortality or cardiovascular morbidity.

      pearl

    expand and show 2 more articles

       

    Daniel Jolley.

    5 articles.

    Created May 21, 2015, last updated about 10 years ago.

    Private Empty Deleted


    Collection: 14, Score: 1882, Trend score: 0, Read count: 2410, Articles count: 5, Created: 2015-05-21 02:15:50 UTC. Updated: 2015-05-21 04:34:44 UTC.

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    Collected Articles

    • Lancet · Oct 2014

      Randomized Controlled Trial Multicenter Study

      The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial.

      Nitrous oxide use in non-cardiac surgery does not increase the risk of death, cardiovascular complications or wound infection.

      pearl

      read on… or just mark as read…

    • Anesthesiology · Jun 2013

      Randomized Controlled Trial

      Leukocyte DNA damage and wound infection after nitrous oxide administration: a randomized controlled trial.

      Nitrous oxide exposure increases DNA damage which may be associated with increased risk of wound infection after colorectal surgery.

      pearl

      expand abstract… or not…

    • Br J Anaesth · Mar 2014

      Review Meta Analysis

      Does anaesthesia with nitrous oxide affect mortality or cardiovascular morbidity? A systematic review with meta-analysis and trial sequential analysis.

      Available evidence does not support the claim that nitrous oxide affects mortality or cardiovascular morbidity.

      pearl

      expand abstract… or not…

    • Anesthesiology · May 2014

      Meta Analysis

      Nitrous Oxide-related Postoperative Nausea and Vomiting Depends on Duration of Exposure.

      Post-op nausea & vomiting incidence is related to duration of nitrous oxide exposure, but is clinically insignificant at under 1 hour exposure.

      pearl

      expand abstract… or not…

    • Anesthesia and analgesia · May 2013

      Randomized Controlled Trial Multicenter Study

      Nitrous oxide and serious morbidity and mortality in the POISE trial.

      Nitrous oxide exposure was not associated with 30-day MI, stroke, death or hypotension in an observational analysis of POISE subjects.

      pearl

      explore further… or not…

    Add articles to this collection...

    collapse collection…


Loading...

Welcome to metajournal!

Sign up for your free metajournal

Receive a weekly email with the highest quality and most significant abstracts from critical care specialties.

Anesthesiology, Critical Care Medicine, Emergency Medicine, Medicine, and Pain medicine.

Includes a free 21 day trial of metajournal premium

  • Personalized abstracts
  • Institutional full-text access
  • Article collections
  • Save favorite articles
  • CME audit reports
  • Journal clubs and more...

We guarantee your privacy. Your email address will not be shared. Unsubscribe anytime.

No thanks, I'm up to date...
metajournal.com @themetajournal by @djoll · Privacy Policy · Terms of Service · v2.0.1
  • About
  • ·
  • Contact
  • ·
  • Pricing
  • ·
  • Help
  • ·
  • FAQ
  • ·
  • Blog
Copyright © 2025 Metajournal Pty Ltd. ACN 600 504 363. ABN 47 600 504 363. Hobart TAS, AUSTRALIA.
Publication data is provided by the National Library of Medicine and PubMed. Please refer to the NCBI's Disclaimer and Copyright notice.