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  Is intrathecal morphine beneficial?

  Intrathecal Morphine Opioid

   
  • Meta Analysis

    Opioids added to local anesthetics for single-shot intrathecal anesthesia in patients undergoing minor surgery: a meta-analysis of randomized trials.

    Pain. 2012 Apr 1;153(4):784-93.

    Intrathecal morphine prolongs post-operative analgesia, but at the expense of increasing nausea, vomiting, pruritus, urinary retention and risk of respiratory depression.

    pearl

  • Observational Study

    Transcutaneous Carbon Dioxide Measurements in Women Receiving Intrathecal Morphine for Cesarean Delivery: A Prospective Observational Study.

    Anesth. Analg. 2017 Mar 1; 124 (3): 872-878.

    Hypercapnia events are common in women receiving 150 mcg intrathecal morphine for cesarean delivery, although clinical significance is uncertain.

    pearl

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  Perioperative & Regional Dexmedetomidine

  Dexmedetomidine

   
  • Review

    Facilitatory effects of perineural dexmedetomidine on neuraxial and peripheral nerve block: a systematic review and meta-analysis.

    Br J Anaesth. 2013 Jun 1; 110 (6): 915-25.

  • Randomized Controlled Trial

    Dexmedetomidine Added to Ropivacaine Extends the Duration of Interscalene Brachial Plexus Blocks for Elective Shoulder Surgery When Compared with Ropivacaine Alone: A Single-Center, Prospective, Triple-Blind, Randomized...

    Reg Anesth Pain Med. 2014 Jan 1; 39 (1): 37-47.

    Dexmedetomidine 150 mcg significantly extends the duration of ropivacaine interscalene block by almost 30% without significant adverse effect.

    pearl

  • Review

    Dexmedetomidine: review, update, and future considerations of paediatric perioperative and periprocedural applications and limitations.

    Br J Anaesth. 2015 Aug 1; 115 (2): 171-82.

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  Retracted anesthesia & perioperative medicine publications

  Collection

   

  Metajournal now automatically tracks and can filter for retracted articles – simply hit search in your article view and filter by article type. Easily check if there are any retracted articles among those you’ve favourited or read previously.

  It’s a sad indictment on a minority in the medical community that this kind of technology is now necessary...

  comment

  
  ...and 1 more note

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  • Review

    Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques.

    J Bone Joint Surg Am. 2007 Jun 1;89(6):1343-58.

  • Randomized Controlled Trial

    Evaluation of the safety and efficacy of the perioperative administration of rofecoxib for total knee arthroplasty.

    J Arthroplasty. 2002 Jan 1;17(1):26-31.

  • Randomized Controlled Trial

    Ramosetron compared with granisetron for the prevention of vomiting following strabismus surgery in children.

    Br J Ophthalmol. 2001 Jun 1;85(6):670-2.

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  Use of cuffed endotracheal tubes in pediatric anesthesia

  Airway Anesthesia Intubation Pediatric anesthesia

   

  Modern cuffed endotracheal tubes are a superior airway device for children and neonates, offering better ventilation mechanics, fewer tube changes, and fewer short-term respiratory complications, with no clinically significant downside.

  pearl

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  • Comment

    Cuffed tracheal tubes: guilty now proven innocent.

    Anaesthesia. 2019 Sep 1; 74 (9): 1186-1190.

  • Randomized Controlled Trial

    Cuffed vs. uncuffed tracheal tubes in children: a randomised controlled trial comparing leak, tidal volume and complications.

    Anaesthesia. 2018 Feb 1; 73 (2): 160-168.

    Cuffed paediatric endotracheal tubes improve ventilation and reduce peri-operative respiratory complications in children undergoing elective general anaesthesia.

    pearl

  • Article

    Work of breathing for cuffed and uncuffed pediatric endotracheal tubes in an in vitro lung model setting.

    Paediatr Anaesth. 2018 Sep 1; 28 (9): 780-787.

    Although cuffed paediatric endotracheal tubes increase work-of-breathing and inspiratory pressures, this is easily compensated for by pressure support ventilation with automatic tube compensation, and so has limited clinical significance.

    pearl

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  Random Stuff

  Collection

   
  • Article

    Why most published research findings are false.

    PLoS Med. 2005 Aug 1; 2 (8): e124e124.

  • Comparative Study

    Lidocaine Preferentially Inhibits the Function of Purinergic P2X7 Receptors Expressed in Xenopus Oocytes.

    Anesth. Analg. 2015 Mar 1; 120 (3): 597-605.

  • Review

    Perioperative acupuncture modulation: more than anaesthesia.

    Br J Anaesth. 2015 Aug 1; 115 (2): 183-93.

  expand and show 6 more articles