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  Is anaesthesia-related neurotoxicity significant in young children?

  Anesthesia Pediatric anesthesia Postoperative complications

   
  • Review

    Perioperative central nervous system injury in neonates.

    Br J Anaesth. 2012 Dec 1;109 Suppl 1:i60-i67.

  • Review

    Anesthesia for the young child undergoing ambulatory procedures: current concerns regarding harm to the developing brain.

    Curr Opin Anaesthesiol. 2013 Dec 1;26(6):677-84.

    Anesthesia neurotoxicity may affect the developing human brain, however methodological challenges limit the conclusiveness of current evidence.

    pearl

  • Review

    Anesthesia-related neurotoxicity and the developing animal brain is not a significant problem in children.

    Paediatr Anaesth. 2015 Jan 1;25(1):65-72.

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  Are suggestion techniques and hypnosis useful in anesthesiology?

  Analgesia Anesthesia Hypnosis

   
  • Review

    Hypnosis, anesthesia, pain management, and preparation for medical procedures.

    Ann Palliat Med. 2019 Sep 1; 8 (4): 498-503.

  • Article

    Hypnosis and anesthesia: back to the future.

    Minerva Anestesiol. 2016 Dec 1; 82 (12): 1343-1356.

  • Review

    Hypnosis for Acute Procedural Pain: A Critical Review.

    Int J Clin Exp Hypn. 2016 Jan 1; 64 (1): 75-115.

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  Hydroxylethyl starches: harm and acute liver injury

  Anesthesia Critical care Fluids Resuscitation

   

  Hydroxyethyl starches, such as Hespan, Voluven, Volulyte, Tetrahes and Hestar, have been shown in several large trials to increase the risk of acute kidney injury (AKI) and/or the need for renal replacement therapies among critically ill patients, particulalry those suffering sepsis.

  Evidence demonstrating harm among fit & healthy surgical patients is however lacking, notably Giles et al could find no increased risk of adverse event among surgical patients in their 2014 meta-analysis. Nonetheless, given the similar lack of demonstrable benefit of HES fluids for this group, avoidance of use in both the ICU and surgical population is prudent.

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  • Comparative Study

    Hydroxyethyl Starch and Acute Kidney Injury in Orthotopic Liver Transplantation: A Single-Center Retrospective Review.

    Anesth. Analg.. 2015 Mar 1;120(3):619-26.

  • Review

    Randomised trials of 6% tetrastarch (hydroxyethyl starch 130/0.4 or 0.42) for severe sepsis reporting mortality: systematic review and meta-analysis.

    Intensive Care Med. 2013 May 1; 39 (5): 811-22.

  • Review

    Incidence of postoperative death and acute kidney injury associated with i.v. 6% hydroxyethyl starch use: systematic review and meta-analysis.

    Br J Anaesth. 2014 Jan 1;112(1):25-34.

    Use of 6% HES solutions in surgical patients is not associated with either harm or benefit in terms of mortality, renal replacement or kidney injury.

    pearl

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  Professionalism in anesthesia and medicine

  Anesthesia Decision making Professionalism

   
  • Review

    Physician professional behaviour affects outcomes: a framework for teaching professionalism during anesthesia residency.

    Can J Anaesth. 2011 Nov 1;58(11):1039-50.

  • Article

    Priorities for professionalism: what do surgeons think?

    Med. J. Aust.. 2015 May 4;202(8):433-7.

  • Article

    The role of maintenance of certification programs in governance and professionalism.

    JAMA. 2015 May 12;313(18):1809-10.

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  Landmark obstetric anesthesia papers

  Anesthesia Epidural Intrathecal Obstetric anesthesia

   

  A collection of landmark research articles relevant to obstetric anesthesia. Some, such as Hawkins' audits of U.S. maternal deaths, are significant because of their historical impact. Others hold direct clinical relevance for practice today.

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  • Article

    Anesthesia-related deaths during obstetric delivery in the United States, 1979-1990.

    Anesthesiology. 1997 Feb 1;86(2):277-84.

  • Article

    Anesthesia-related maternal mortality in the United States: 1979-2002.

    Obstet Gynecol. 2011 Jan 1;117(1):69-74.

  • Article

    Difficult and failed intubation in obstetric anaesthesia: an observational study of airway management and complications associated with general anaesthesia for caesarean section.

    Int J Obstet Anesth. 2008 Oct 1;17(4):292-7.

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