International journal of clinical practice
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisThe Effects of Pharmacological Interventions on Smoking Cessation in People with Alcohol Dependence: A Systematic Review and Meta-analysis of Nine Randomized Controlled Trials.
Pharmacotherapies are widely used for smoking cessation. However, their efficacy for people with alcohol dependence remains unclear. ⋯ Varenicline may promote smoking cessation in people with alcohol dependence. However, Naltrexone, Topiramate and Bupropion have no clear effect on increasing smoking abstinence among drinkers. The small number of studies and the low certainty of evidence indicate that the results should be interpreted cautiously.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisThe association between psoriasis and psoriatic arthritis with the risk of osteoporosis, osteopenia, and bone fractures: a systematic review and meta-analysis.
The possible association between psoriatic/psoriatic arthritis (PsA) and bone loss has been observed; however, studies have yielded inconclusive results. This meta-analysis aimed to assess whether there is an increase in the risk of osteoporosis, osteopenia and fractures in patients with psoriasis/PsA, compared with healthy individuals. ⋯ Patients with psoriasis/PsA have an increased risk of fractures. There is little evidence supporting the relation of psoriasis to osteoporosis/osteopenia.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisComparison of efficacy and safety of gabapentin and duloxetine in painful diabetic peripheral neuropathy: A systematic review and meta-analysis of randomized controlled trials.
In patients with diabetes mellitus, painful diabetic peripheral neuropathy (PDPN) is a frequent complication and can cause poor quality of life. We compared the efficacy and safety of duloxetine with those of gabapentin in patients with PDPN through a systematic review and meta-analysis of randomised controlled trials. ⋯ No significant differences were observed in the efficacy of duloxetine and gabapentin when treating patients with PDPN.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisAccuracy of pecarn decision rule in minor blunt head trauma in pediatric emergency department: A meta-analysis.
Paediatric Emergency Care Applied Research Network (PECARN) is a useful Clinical Decision Support Tool (CDST) to identify traumatic brain injuries and reduce the use of head computed tomography (CT) scans among paediatric patients. The present Meta-analysis aims to evaluate the diagnostic accuracy of the PECARN rule from 2009 to 2020 in children with a very low risk of blunt head trauma. ⋯ The present analysis indicates the PECARN decision tool as an accurate CDST in low-risk minor BHT cases in children below two years of age and can become a valuable tool in reducing Head CT scan overuse in paediatric emergency departments.
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Int. J. Clin. Pract. · Nov 2021
ReviewThe Impact of Pharmacy Care and Motivational Interviewing on improving medication adherence in patients with cardiovascular diseases: A Systematic Review of Randomised Controlled Trials.
Cardiovascular disease (CVD) is prevalent worldwide, and for many patients, non-adherence to medication remains a problem. Motivational interviewing is a behavioural, communication strategy used as an intervention aimed to improve health outcomes. ⋯ Motivational interviewing could be an effective behavioural strategy to enhance medication adherence in patients with CVD. Although the evidence is promising thus far, further research is required to explore the impact of motivational interviewing on clinical outcomes as well as the feasibility of implementing motivational interviewing interventions within existing pharmacy care services.