International journal of clinical practice
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Int. J. Clin. Pract. · Nov 2021
Letter Review Meta AnalysisPrevalence of comorbid tuberculosis amongst COVID-19 patients: A rapid review and meta-analysis.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisThe Role of Vitamin D in the Age of COVID-19: A Systematic Review and Meta-Analysis.
Evidence recommends that vitamin D might be a crucial supportive agent for the immune system, mainly in cytokine response regulation against COVID-19. Hence, we carried out a systematic review and meta-analysis in order to maximise the use of everything that exists about the role of vitamin D in the COVID-19. ⋯ This study found that most of the COVID-19 patients were suffering from vitamin D deficiency/insufficiency. Also, there is about three times higher chance of getting infected with SARS-CoV-2 among vitamin-D-deficient individuals and about five times higher probability of developing the severe disease in vitamin-D-deficient patients. Vitamin D deficiency showed no significant association with mortality rates in this population.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisCrimean-Congo hemorrhagic fever-induced liver injury: a systematic review and meta-analysis.
Crimean-Congo haemorrhagic fever (CCHF) is a fatal acute tick-borne viral infection and substantial emerging global public health threat. This illness has a high case fatality rate of up to 40%. The liver is one of the important target organs of the CCHF virus. ⋯ Our study shows that CCHF has a very detrimental effect on liver function. Abnormal liver function may lead to poor prognosis and increased morbidity and mortality in CCHF patients. Hence, Physicians must recognise and continuously monitor these biomarkers, since these markers may aid in early stratification of prognosis and the prevention of severe outcomes in infection with such a high case fatality rate.
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Int. J. Clin. Pract. · Nov 2021
ReviewVitamin D recommendations in clinical guidelines: A systematic review, quality evaluation and analysis of potential predictors.
Vitamin D has been widely promoted for bone health through supplementation and fortification of the general adult population. However, there is growing evidence that does not support these strategies. Our aim is to review the quality and recommendations on vitamin D nutritional and clinical practice guidelines and to explore predictive factors for their direction and strength. ⋯ Policymakers, clinicians and patients should be aware that lower quality guidelines and those reporting conflicts of interest are more likely to promote vitamin D supplementation. Guideline organisations should improve the quality of their recommendations' development and the management of conflicts of interest. Users and editors should be aware of these findings when using and appraising guidelines.
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Int. J. Clin. Pract. · Nov 2021
Meta AnalysisSleep-disordered breathing and risk of the breast cancer: a meta-analysis of cohort studies.
Sleep-disordered breathing (SDB) has been related to a higher risk of breast cancer whereas the results of previous studies are inconsistent. We, therefore, performed a meta-analysis to evaluate the association between SDB and subsequent risk of breast cancer in women. ⋯ SDB may be an independent risk factor for breast cancer in women, particularly in elderly females.