International journal of clinical practice
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To evaluate the bowel habits of patients with acne vulgaris. ⋯ Further large sample sized studies are needed on this subject, as there is strong evidence about brain-gut-skin axis existence.
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Int. J. Clin. Pract. · Dec 2021
Reconstruction of Achilles region defects: a single-center experience.
Reconstruction of Achilles tendon and the overlying tissue defects is a challenging undertaking. The spectrum of available repair methods range from secondary healing to the use of free flaps. The aim of this study was to discuss reconstruction options and to help the surgeon to select reliable approach to achieve favourable outcomes. ⋯ Orthoplastic reconstruction should be kept in mind for Achilles tendon defects. The use of special digital imaging techniques facilitates flap surgery and helps minimise the risk of flap complications. Conventional approaches are suitable for shallow small skin lesions. Local flaps are good options for deeper skin defects owing to superior aesthetic outcomes. Super-thin free flaps offer a distinct advantage in skillful hands. The use of multi-content free chimeric flaps for reconstruction of complex defects facilitates better anatomical repair. Cross leg or flow-through flaps may be considered in patients with compromised distal circulation. Selection of the most reliable approach for Achilles reconstruction is a key imperative to achieve favourable outcomes.
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Int. J. Clin. Pract. · Dec 2021
Expression of Leptin mRNA as Non-Invasive Biomarker in Type 2 Diabetes Mellitus.
Leptin, an adipocyte-derived signalling molecule that plays important role in the regulation of energy balance, body weight and glucose metabolism. ⋯ This study shows that the reduced leptin mRNA expression level is significantly associated with T2DM and could be used as a predictive and diagnostic biomarker for T2DM.
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Int. J. Clin. Pract. · Dec 2021
Correlation of Racial Effect with Severity of Disease and In-Hospital Outcome in Individuals Diagnosed with COVID-19.
There are many countries that inhibit diverse populations and hence, studies have been conducted to find the relation between ethnic and racial groups within a society and incidence or mortality because of coronavirus disease-19 (COVID-19). ⋯ Severity and in-hospital outcome were varying considerably amongst the racial groups. East and South Asian COVID-19 patients had more severe symptoms and less recovery rate compared with other groups, late presentation may be a contributory reason. Hence, evaluation of the severity of COVID-19 in relation to the various racial groups along with demographic characteristics and other risk factors can provide baseline guidance to the clinical care providers to initiate earlier and appropriate treatment.
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Int. J. Clin. Pract. · Dec 2021
Primary primitive neuroectodermal tumor of the kidney in adults: experience of managing 12 cases with systematic review and pooled analysis of literature.
Primitive neuroectodermal tumor (PNET) of the kidney is unusual in adults. These tumours are diagnosed mainly on histopathology and that too sometimes has limitations. With this study, we aimed to review our clinical and histopathological data of patients with renal PNET and reviewing the world literature. ⋯ PNET remains a pathological diagnosis and IHC has important place in diagnosis of PNET. Locally advanced and metastatic disease is common at diagnosis leading to overall poor survival.