International journal of clinical practice
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Int. J. Clin. Pract. · Dec 2021
Impact of Urinary Incontinence on Physical Performance and Quality of Life (QOL) Among a Group of Elderly in Cairo.
Urinary incontinence (UI), involuntary loss of urine, is a common disorder affecting the elderly population worldwide. UI can be associated with poor quality of life (QOL) in this vulnerable population, as it limits both physical and social activities of daily living (ADLs). Additionally, it has a psychological and economic burden on individuals, healthcare services and society. This study was conducted to measure the frequency of UI amongst the elderly and determine its impact on the overall QOL, physical performance, and ADLs. ⋯ UI has a high prevalence rate amongst elderly individuals and significantly affects all aspects of QOL, especially physical performance.
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Int. J. Clin. Pract. · Dec 2021
Children With Appendectomy Have Increased Risk of Future Sepsis: Real-world Data in Taiwan.
Appendectomy is one of the most commonly performed surgeries worldwide. Sepsis is a major aetiology of morbidity and mortality in children. Our preliminary research revealed a positive correlation amongst appendectomy and future risk of sepsis in adults. However, to date, the relationship between appendectomy and future risk of sepsis in children remains unknown. The aim of this research was to investigate the relationship between appendectomy and the hazard of future sepsis in children. ⋯ Appendectomy was correlative to a 2.38-fold increased future sepsis risk in children, and the risk in all age groups was higher. More studies to interpret the possible biological mechanisms of the associations amongst sepsis and appendectomy are warranted.
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Int. J. Clin. Pract. · Dec 2021
The safety profile of favipiravir in COVID-19 patients with severe renal impairment.
The safety profile of favipiravir in patients with severe renal impairment has not been investigated and available data are insufficient. The study aimed to compare the incidence of favipiravir-associated adverse events amongst patients with varying renal function statuses. ⋯ Even though favipiravir appeared to be well tolerated in the individuals with renal failure in this study, its use in this population remains a challenge that requires more research and analysis.
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Int. J. Clin. Pract. · Dec 2021
Organ-specific autoimmune markers in adult patients with type 1 diabetes mellitus.
We aimed to investigate the presence of thyroid, celiac disease (CD) and anti-parietal cell antibodies (APCA) in adult type 1 diabetes (T1DM) patients. ⋯ Almost half of the adult T1DM patients were positive for at least one non-diabetic antibody. It is important to investigate thyroid autoimmunity in patients diagnosed with T1DM at any age, including advanced age. CD associated antibody positivity increases with disease duration, suggesting that they should be re-evaluated at clinical suspicion, even if prior tests were negative.
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Int. J. Clin. Pract. · Dec 2021
Sex differences in electrolyte imbalances caused by SARS-CoV-2: a cross-sectional study.
Since SARS-CoV-2 spread, evidence regarding sex differences in progression and prognosis of COVID-19 have emerged. Besides this, studies on patients' clinical characteristics have described electrolyte imbalances as one of the recurrent features of COVID-19. ⋯ SARS-CoV-2 infection is associated with a higher prevalence of hypokalaemia, hypocalcaemia, hypochloraemia and sodium alterations. Hypokalaemia is more frequent among women and hypocalcaemia among men.