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Randomized Controlled Trial Multicenter Study Clinical Trial
Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial.
BIS monitoring significantly reduces the risk of awareness under general anesthesia in high-risk adult surgical patients.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Epidural anaesthesia and analgesia and outcome of major surgery: a randomised trial.
Perioperative epidural analgesia in high-risk patients undergoing major abdominal surgery improves analgesia but does not have other morbidity or mortality benefits.
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Randomized Controlled Trial Multicenter Study Comparative Study
Incidence and duration of residual paralysis at the end of surgery after multiple administrations of cisatracurium and rocuronium.
After repeated rocuronium administration there is wide inter-patient variability in the time to recover muscle function.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network.
Traditional approaches to mechanical ventilation use tidal volumes of 10 to 15 ml per kilogram of body weight and may cause stretch-induced lung injury in patients with acute lung injury and the acute respiratory distress syndrome. We therefore conducted a trial to determine whether ventilation with lower tidal volumes would improve the clinical outcomes in these patients. ⋯ In patients with acute lung injury and the acute respiratory distress syndrome, mechanical ventilation with a lower tidal volume than is traditionally used results in decreased mortality and increases the number of days without ventilator use.
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Randomized Controlled Trial Multicenter Study
Effect of the World Health Organization checklist on patient outcomes: a stepped wedge cluster randomized controlled trial.
Implementing the WHO Safe Surgery Checklist may reduce morbidity, length of stay and mortality, although many questions remain.
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