Either proximal or distal sciatic nerve block reduces pain in the first 6 hours after total knee arthroplasty. Distal (popliteal) may be superior.
I find the existence of this study perplexing. This meta-analysis appears to simply confirm basic neuromuscular pharmacology and age-related cardiovascular changes. The unanswered question is why are they so interested in using mivacurium anyway?
I conclude that good conditions for tracheal intubation are more likely when using a muscle relaxant other than mivacurium.
Intraoperative ketamine and magnesium improves post-operative analgesia after scoliosis surgery when compared to ketamine alone.
Dexamethasone 8 mg has equal effect in prolonging single-shot supraclavicular block whether given perineurial or intravenously.
Intraoperative intravenous lidocaine improves the quality of recovery following ambulatory laparoscopic surgery.
Intrathecal fentanyl synergistically improves labour analgesia when given in combination with bupivacaine.
Pulsed radiofrequency stimulation of the suprascapular nerve improves pain and range of motion in those with adhesive capsulitis.
Peri-operative melatonin may cause small reductions in pre-operative anxiety and post-operative pain.
Periarticular infiltration with ropivacaine and ketorolac provides equivalent and likely superior post-op analgesia to intrathecal morphine after THA.
Despite the statistical significance of this finding, I question the clinical significance and appropriateness – especially in the context of ongoing questions regarding the safety of HES solutions and given there are alternative interventions also shown to reduce symptomatic hypotension in this setting.