Articles: pediatrics.
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Meta Analysis
Dexmedetomidine in combination with ketamine for pediatric procedural sedation or premedication: A meta-analysis.
To evaluate effectiveness of combinational use of dexmedetomidine and ketamine (DEX-KET) for pediatric procedural sedation or premedication. ⋯ DEX-KET for pediatric sedation results in better sedation outcomes than DEX or KET by shortening onset of sedation and recovery while maintaining hemodynamic and respiratory stability with low incidence of adverse events. DEX sedation was associated with higher incidence of bradycardia. Higher incidence of oxygen desaturation was observed with KET and PROP-KET whereas MIDA-KET was associated with higher incidence of tachycardia.
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The comparison of ketamine with fentanyl for pain control of pediatric orthopedic emergencies remains controversial. We conduct a systematic review and meta-analysis to explore the influence of ketamine versus fentanyl on pain management among pediatric orthopedic emergencies. ⋯ Ketamine may be similar to fentanyl in terms of the analgesic efficacy for pediatric orthopedic emergencies.
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Meta Analysis
Computed tomography features of COVID-19 in children: A systematic review and meta-analysis.
There are few reports on the chest computed tomography (CT) imaging features of children with coronavirus disease 2019 (COVID-19), and most reports involve small sample sizes. ⋯ The lung CT results of children with COVID-19 are usually normal or slightly atypical. The lung lesions of COVID-19 pediatric patients mostly involve both lungs or multiple lobes, and the common manifestations are patchy shadows, ground-glass opacities, consolidation, partial air bronchogram signs, nodules, and halo signs; white lung, pleural effusion, and paving stone signs are rare. Therefore, chest CT has limited value as a screening tool for children with COVID-19 and can only be used as an auxiliary assessment tool.
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Review Meta Analysis
The prevalence of serious bacterial infections in neutropenic immunocompetent febrile children.
Febrile neutropenic immunocompromised children are at a high risk of Serious Bacterial Infections (SBI). ⋯ If the clinical suspicion is low, the risk for SBI is similar between febrile healthy neutropenic and non-neutropenic children.