Propofol and ketamine are acceptable either alone or in combination for pediatric procedural sedation.
Intubation in microgravity by novices was more successful using videolaryngoscopy than direct laryngoscopy.
Goal-directed fluid therapy offered no benefit over standard therapy in patients undergoing open radical cystectomy, although was associated with a higher incidence of acute kidney injury.
Among infants & children < 3y having prone general anaesthesia, regular hourly alveolar recruitment reduces pre-extubation atelectasis.
More on the Clinical Frailty Score at the NHS' Specialised Clinical Frailty Network.
The Clinical Frailty Scale provides meaningful additional outcome prediction to traditional preoperative risk factors among non-cardiac surgery patients.
Remifentanil does not reduce the performance of BIS-based closed-loop propofol anesthesia with a remifentanil effect site concentration of 2.8-7.5 ng/mL.
Pediatric airway management guidelines for COVID-19 patients relies upon non-clinical studies, infectious disease data and expert opinion.
The analgesic benefit and safety of pre-hospital femoral nerve block compared with other, more common forms of pain-relief remains uncertain.
Neither perioperative aspirin or clonidine show long-term benefit in terms of death, cardiovascular complication, cancer, or chronic pain at 1 year, except for a benefit of aspirin for patients with a history of PCI.