Pre-spinal-anaesthesia administration of IV ondansetron 4 mg reduces the ED50 of prophylactic phenylephrine infusion by 26% among patients undergoing elective Caesarean section.
High-inspired 80% FiO2 shows no safety compromise when compared with standard 30-35% FiO2 among surgical patients.
Left-lateral tilt has no effect on neonatal acid-base status when maternal blood pressure is maintained with crystalloid coload & phenylephrine infusion during elective cesarean delivery.
Phenylephrine & noradrenaline show similar incidence of bradycardia when used for postspinal hypotension prophylaxis during Caesarean section.
Preeclampsia diagnostic technologies continue to advance. Peripartum care is improved with multidisciplinary teams, specialist anaesthesia care and the availability of critical care support.
Closed-loop goal-directed fluid therapy with colloids is associated with lower volume infused and fewer postoperative complications than with crystalloids.
Perineural dexamethasone prolongs interscalene block in a dose-dependent way between doses of 1 to 4 mg.
Peri-operative hyperbaric oxygen therapy is associated with a range of outcome improvements, including various surgical-recovery and peri-operative indices.
Spinal anaesthesia for Caesarean section in patients with COVID can be provided safely, although anaesthetists are at risk of infection, significantly reduced by use of Level 3 PPE (PAPR + protective suit).
The Clinical Frailty Scale is the most feasible frailty measure and has the strongest association with mortality and non-favourable discharge.