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pearl
1
Among infants & children < 3y having prone general anaesthesia, regular hourly alveolar recruitment reduces pre-extubation atelectasis.
Jang YE, Ji SH, Kim EH et al. Effect of regular alveolar recruitment on intraoperative atelectasis in paediatric patients ventilated in the prone position: a randomised controlled trial. Br J Anaesth. 2020 May 1; 124 (5): 648-655.
  Daniel Jolley
comment
1
More on the Clinical Frailty Score at the NHS' Specialised Clinical Frailty Network.

McIsaac DI, Harris EP, Hladkowicz E et al. Prospective Comparison of Preoperative Predictive Performance Between 3 Leading Frailty Instruments. Anesth. Analg. 2020 Jul 1; 131 (1): 263-272.
  Daniel Jolley
pearl
1
The Clinical Frailty Scale provides meaningful additional outcome prediction to traditional preoperative risk factors among non-cardiac surgery patients.
McIsaac DI, Harris EP, Hladkowicz E et al. Prospective Comparison of Preoperative Predictive Performance Between 3 Leading Frailty Instruments. Anesth. Analg. 2020 Jul 1; 131 (1): 263-272.
  Daniel Jolley
pearl
1
Remifentanil does not reduce the performance of BIS-based closed-loop propofol anesthesia with a remifentanil effect site concentration of 2.8-7.5 ng/mL.
Neckebroek M, JHL Boldingh, De T et al. Influence of Remifentanil on the Control Performance of the Bispectral Index Controlled Bayesian-Based Closed-Loop System for Propofol Administration. Anesth. Analg. 2020 Jun 1; 130 (6): 1661-1669.
  Daniel Jolley
pearl
1
Pediatric airway management guidelines for COVID-19 patients relies upon non-clinical studies, infectious disease data and expert opinion.
Matava CT, Kovatsis PG, Lee JK et al. Pediatric Airway Management in COVID-19 patients - Consensus Guidelines from the Society for Pediatric Anesthesia's Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society. Anesth. Analg. 2020 Jul 1; 131 (1): 61-73.
  Daniel Jolley
pearl
1
The analgesic benefit and safety of pre-hospital femoral nerve block compared with other, more common forms of pain-relief remains uncertain.
Raatiniemi L, Magnusson V, Hyldmo PK et al. Femoral nerve blocks for the treatment of acute prehospital pain: a systematic reviewwith meta-analysis. Acta Anaesthesiol Scand. 2020 Sep 1; 64 (8): 1038-1047.
  Daniel Jolley
pearl
1
Neither perioperative aspirin or clonidine show long-term benefit in terms of death, cardiovascular complication, cancer, or chronic pain at 1 year, except for a benefit of aspirin for patients with a history of PCI.
Sessler DI, Conen D, Leslie K et al. One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery. Anesthesiology. 2020 Apr 1; 132 (4): 692-701.
  Daniel Jolley
pearl
1
Sugammadex showed no benefit over neostigmine when assessed using PACU spirometry, muscle strength, TOFR or other indicators of recovery up to 2 hours post-reversal.
Abola RE, Romeiser J, Rizwan S et al. A randomized-controlled trial of sugammadex versus neostigmine: impact on early postoperative strength. Can J Anaesth. 2020 Aug 1; 67 (8): 959-969.
  Daniel Jolley
pearl
1
Careful planning and preparation before emergency cesarean section for COVID-19 infected parturient is essential to reduce healthcare worker infection and ensure mother & infant safety.
Du Y, Wang L, Wu G et al. Anesthesia and protection in an emergency cesarean section for pregnant woman infected with a novel coronavirus: case report and literature review. J Anesth. 2020 Aug 1; 34 (4): 613-618.
  Daniel Jolley
pearl
1
Neurally-adjusted ventilatory assist improves patient-ventilator synchrony although with uncertain effect on clinical outcome..
Pettenuzzo T, Aoyama H, Englesakis M et al. Effect of Neurally Adjusted Ventilatory Assist on Patient-Ventilator Interaction in Mechanically Ventilated Adults: A Systematic Review and Meta-Analysis. Crit. Care Med. 2019 Jul 1; 47 (7): e602-e609.
  Daniel Jolley